Basic HTML Version
Course
Pro-forma
Bachelor of Engineering (Chemical)
Code
KKEK4311
Title
Biochemical Engineering
Pre-requisite
KKEK 3151 Biochemistry
Student Learning Time (SLT)
80 hours
Credit
2
Learning Outcomes
1.
Employ calculations for enzymatic reactions in biochemical
systems.
2.
Employ calculations in bio-processing by applying the
chemical engineering approaches in nomenclature and
mathematical analysis.
3.
Analyze growth kinetics based on structured models.
4.
Discuss the importance of agitation and aeration to achieve
adequate mixing for the design of bioreactors.
5.
Discuss different sterilization methods and their suitability in
bioprocesses.
6.
Analyze bio-products and to select the suitable technique for
bio-separation.
Synopsis
This course introduces the fundamental principle of Biochemical
Engineering. The enzyme kinetics and the factors influencing of
the enzyme activities are emphasized and so are the immobilized
enzymes and the methods of immobilization. The course also
covers the growth kinetics and modelling of the growth system,
various operation modes of bioreactors, types of conventional
and novel bioreactors. Different methods of sterilization, kinetics
of thermal deactivation and design of heat sterilization cycle are
also included. A brief coverage on the dimensional analysis as
principle for scaling up is given before the course is extended to
the selection of suitable downstream processes and the
characterization of the fermentation products.
Assessment
40 % Continuous Assessments
60 % Final Examination
References
1.
J.M. Lee Biochemical Engineering, Prentice Hall, 1992.
2.
M.L. Shuler and F. Kargi, Bioprocess Engineering: Basic
Concepts, Prentice Hall, 1992.
3.
J. Bailey and D. Ollis, Biochemical Engineering
Fundamentals, 1986, McGraw Hill.
4.
N. Blakebrough, Biochemical and Biological Engineering
Science, 1967, Academic Press.
5.
M. J. Asenjo, J. Merchuk and M. Dekker, Bioreactor System
Design, 1995.
Soft Skills
Communication skills (CS1, CS2, CS3)
Critical thinking and problem solving skills (CT1, CT2, CT3)